Isolation and characterization of an olfactory receptor protein for odorant pyrazines.
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چکیده
منابع مشابه
An odorant derivative as an antagonist for an olfactory receptor.
Different odorants are recognized by different combinations of G protein-coupled olfactory receptors, and thereby, odor identity is determined by a combinatorial receptor code for each odorant. We recently demonstrated that odorants appeared to compete for receptor sites to act as an agonist or an antagonist. Therefore, in natural circumstances where we always perceive a mixture of various odor...
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The perception and discrimination of thousands of different odorants by the vertebrate olfactory system results from the activation of specific olfactory neurons within the olfactory epithelium of the nose (reviewed in Buck, 2000; Firestein, 2001). Activity from these cells is then interpreted by the brain to discern the molecular identity of a given odorant stimulus. How is this process of mol...
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15 صفحه اولIsolation and characterization of rat olfactory marker protein.
The olfactory marker protein was isolated and characterized from rat olfactory bulbs. Its properties and those of the olfactory marker protein isolated from the mouse are described. The rat protein was less acidic (pI = 5.0) than the mouse protein (pI = 4.7). However, the amino acid compositions were very similar: in both proteins arginine plus lysine accounted for 13 mol% and glutamate plus as...
متن کاملOdorant response properties of convergent olfactory receptor neurons.
Information about odorant stimuli is thought to be represented in spatial and temporal patterns of activity across neurons in the olfactory epithelium and the olfactory bulb (OB). Previous studies suggest that olfactory receptor neurons (ORNs) distributed in the nasal cavity project to localized regions in the glomerular layer of the OB. However, the functional significance of this convergence ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1985
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.82.9.3050